Lidocaine 5% Spray with Phenylephrine 0.25%, 6 fl oz
$18 per 6 fl oz bottle per 6 fl oz bottle
Our lidocaine spray 5% provides the strongest over-the-counter lidocaine for numbing relief with an extra ingredient to help reduce swelling.
Active Ingredient: Lidocaine spray 5% with phenylephrine 0.25% , 6 fl oz (177 ml)
-
Lidocaine 5% Strength
-
Spray
-
No Touch Application
-
Value Size
-
Made in USA*
Are You...
Looking for a numbing spray with lidocaine 5%?
*with globally sourced ingredients
Good For
Temporary relief from hemorrhoids and other anorectal issues
Lidocaine 5% for numbing
Phenylephrine 0.25% to reduce swelling
Temporary relief of pain, itching, and burning
Temporarily shrinks hemorrhoidal tissue
Temporarily reduces the swelling associated with irritation in hemorrhoids and other anorectal disorders
Not For
Do not ingest (external use only)
Topical pain relief. Consider Curist Lidocaine 4% Patch for that.
Arthritis relief. Consider Curist Arthritis Relief for that.
Itchiness or discomfort from allergies. Check out our Allergy Collection for that.

Lidocaine Spray 5% with Phenylephrine 0.25%
Why Use Lidocaine Spray for Numbing Relief?
Curist Lidocaine Spray is formulated with lidocaine and phenylephrine, which works to numb pain and reduce swelling. It’s designed to absorb quickly, and the gentle mist allows for a no-touch application, which makes it easier for that area which is hard to reach and may be painful to the touch.
Doctor Pro Tip

“Lidocaine belongs to the family of medicines called local anesthetics. This medicine prevents pain by blocking the signals at the nerve endings in the skin.”
Mayo Clinic
Everything you need to know about lidocaine and phenylephrine
Lidocaine 5% Spray with Phenylephrine 0.25% FAQ
Curist Lidocaine Spray contains lidocaine 5% and phenylephrine 0.25% as its active ingredients. Inactive ingredients in the Curist Lidocaine Spray include aloe barbadensis leaf extract, benzophenone-4, denatured ethyl alcohol, disodium EDTA, ethylhexylglycerin, phenoxyethanol, polysorbate-20, propylene glycol, sodium citrate, tocopheryl acetate, and water.
Lidocaine is a local anesthetic that causes a numbing effect on the area it is applied. Lidocaine comes in different strengths and can be found over-the-counter (OTC) as a cream, patch, or spray.
Lidocaine works by blocking the nerve signals to cause a numbing effect locally in the area it is applied. Please note that lidocaine provides temporary numbing relief, but it does not treat the underlying condition.
Curist Lidocaine Spray 5% with Phenylephrine 0.25% is available OTC to help with itching and pain caused by hemorrhoids.
Phenylephrine works as a topical vasoconstrictor and works to decrease swelling and redness in the area. Phenylephrine is added to Curist Lidocaine Spray to help reduce swelling associated with hemorrhoids. Phenylephrine is also typically found OTC as a nasal spray to relieve congestion.
Lidocaine sprays absorb quickly. Curist Lidocaine Spray can be applied to the affected area up to 3 to 4 times per day.
Curist Lidocaine Spray is generally safe to use for adults and children over 12 years old if it is applied as directed. Avoid applying lidocaine to open wounds, burns, or broken skin and near the eyes. Lidocaine 5% should only be used for hemorrhoids and other anorectal issues. Please consult your doctor before using lidocaine spray if you have a chronic medical condition or are taking a prescription medication. Since it is a spray, Curist Lidocaine Spray should be stored at room temperature away from heat and materials that could puncture the bottle.
Lidocaine spray is sprayed in a gentle mist onto the treatment site. This option may be preferred if the area is painful to the touch or is hard to reach. Lidocaine spray absorbs quickly into the skin and works within minutes.
Lidocaine cream is applied by directly rubbing the cream onto the affected area. Lidocaine cream has a semi-thick consistency that dries without leaving behind a greasy residue. Because creams tend to dry slower than sprays, lidocaine cream may unintentionally be wiped off before it can fully absorb.
Both lidocaine sprays and lidocaine creams can work well to treat symptoms, so ultimately the choice is up to you! To learn more about various lidocaine options, please check out our article Lidocaine Cream vs Lidocaine Ointment vs Lidocaine Patch vs Lidocaine Spray vs Lidocaine Roll On.
The strongest lidocaine spray at the highest percentage available on the market over-the-counter is lidocaine 5% by Curist. Strengths above 5% require a doctor visit and prescription. Curist Lidocaine Numbing Spray contains lidocaine 5%, which is the strongest OTC lidocaine spray available at the highest percentage. Lidocaine 5% is used to treat anorectal or other hemorrhoidal issues.
Yes, lidocaine spray 5% is available over-the-counter without a prescription at Curist. Lidocaine 5% OTC is available to buy online at Curist. Lidocaine 10% is not available over-the-counter.
No, lidocaine 5% spray is not prescription only. Lidocaine 5% is available at Curist without a prescription as a spray and as a cream. Lidocaine 5% patches are only sold as a prescription, though Curist Lidocaine 4% Patches are available over-the-counter.
Yes, Curist Lidocaine 5% Spray with Phenylephrine is HSA eligible and FSA eligible. If you have an HSA or FSA account, you can use those funds by either:
1) Using an HSA or FSA debit card when you check out like you normally would--no other action required! At the Payment step, select "Sika | Pay with HSA/FSA" to enter your debit card information. Sika is a secure, PCI compliant payment gateway that accepts HSA & FSA payments on our behalf.
2) Using another payment method and reimbursing yourself from your HSA or FSA account later. We will automatically email you a receipt that can be submitted for reimbursement.
Eligibility and terms are subject to change in accordance with federal guidelines. Please reach out to us at hi@curistrelief.com if you have any questions.